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39, 40 Current outcomes with non-invasive imaging are remarkably encouraging, specially given that they permit longitudinal evaluations of tumors through the entire study course of therapy. Nonetheless, these techniques are less exact than invasive approaches including the oxygen probe,forty one as PET, MRI and CT usually do not allow for in depth
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Hypoxic cell radiation sensitizers mimic the consequences of oxygen to increase radiation-induced DNA damage. This sort of agents are exceptionally efficient in sensitizing hypoxic cells in vitroeleven The “oxygen impact” wasn't confined to tumor cells in tissue lifestyle. Pre-clinical scientific studies in mice12 demonstrated that even tumors